Cook the penne pasta according to package instructions.
Season the chicken breasts with garlic powder, onion powder, salt, and pepper.
In a skillet over medium heat, cook the seasoned chicken until browned and cooked through, about 6-7 minutes per side.
Remove the chicken from the skillet and chop it into bite-sized pieces.
In the same skillet, add cream cheese, chicken broth, and ranch seasoning over medium heat until melted and smooth.
Stir in cheddar cheese until melted and the sauce is creamy.
Toss the cooked penne and chicken into the creamy sauce, stirring to combine thoroughly.
Serve warm, garnished with additional cheddar or herbs if desired.